Fat Loss & Metabolic Health

Mazdutide vs Retatrutide: Receptors, Trial Data and Where They Differ

Mazdutide and retatrutide are often filed together as “next-generation GLP-1 drugs,” but they are not the same class of molecule and they…

What Is Adipotide (FTPP)? The Fat-Targeting Peptide and What the Research Actually Shows

Adipotide, also called FTPP — a research-chemical abbreviation for fat-targeted proapoptotic peptide — or Prohibitin Targeting Peptide 1, is an experimental peptidomimetic…

What Is Pramlintide? Amylin Analog Pharmacology and Its Approved Role

Pramlintide is a synthetic 37-amino-acid analog of human amylin (islet amyloid polypeptide, IAPP), the second hormone that pancreatic beta cells release alongside…

What Is Tesofensine? Mechanism, Trial Record and Regulatory Status

Tesofensine is not a peptide. It is a small-molecule phenyltropane — a triple monoamine reuptake inhibitor that blocks the noradrenaline, dopamine and…

What Is L-Carnitine? The Carnitine Shuttle and What the Research Actually Shows

L-carnitine is not a peptide. It is a small quaternary ammonium compound (a betaine) that the body builds from the amino acids…

GLP-1 Microdosing: What the Evidence Actually Shows

“GLP-1 microdosing” describes the deliberate use of a GLP-1 receptor agonist at a dose below the approved therapeutic or maintenance range, usually…

Does Tirzepatide Cause Constipation? What the Trial Data and Labels Report

Yes — constipation is a labelled adverse reaction of tirzepatide, and it appears in the FDA-approved prescribing information for both branded products.…

What Is Eloralintide? The Selective Amylin Agonist and What Its Phase 2 Data Show

Eloralintide (development code LY3841136) is Eli Lilly’s investigational once-weekly selective amylin receptor agonist — a synthetic amylin analogue engineered to activate the…

Switching From Tirzepatide to Retatrutide: What the Receptor Data and Trial Designs Imply

The direct answer first: as of August 2026 there is no published clinical trial of switching from tirzepatide to retatrutide, and no…

How Long Does Semaglutide Take to Work? The Week-by-Week Timeline

Quick answerThe drug reaches full exposure in about a month. The results the trials published arrive much later. In the blood: peak…