Dr. Aimen Arij

What Is the Function of MOTS-C in Metabolic Adaptation to Physiological Stress?

The question of what MOTS-c “does” during physiological stress is unusually well-posed compared with most peptide questions, because MOTS-c was discovered as…

Ipamorelin vs Other GH Peptides: How They Compare

Ipamorelin’s distinction is selectivity, not results. It was designed to release growth hormone without the cortisol and prolactin spillover of the earlier…

How Does Selank Influence GABA Signaling to Help Lower Anxiety Levels?

Short answer: the GABA story is weaker than it is usually told. Selank is routinely described as lowering anxiety by modulating GABA…

How Could Semax Affect Neural Circuit Stability During Cognitive Load?

The question at the top of this page — how Semax might affect neural circuit stability during cognitive load — is phrased…

Retatrutide and PCOS: What We Actually Know About Insulin Resistance

The honest answer first. Retatrutide has never been tested in a trial enrolling women with PCOS. Not one. Everything written about “retatrutide…

What Does Research Reveal About BPC-157 Role in Gastrointestinal Ulcer Protection?

Short answer: in rats, BPC-157 prevents and heals gut ulcers with remarkable consistency. In humans, there is nothing. Across three decades of…

Does TB-500 Promote Cellular Migration in Diabetic Non-Healing Wound Models?

Short answer: the evidence does not support it. In the one experiment that tested the question most directly — genetically diabetic db/db…

How Effective Is PT-141 for Sexual Dysfunction Caused by Depression?

PT-141 has never been tested in people whose low libido comes from depression, and the label of the one approved product goes…

How Does AOD-9604 Stimulate Fat Breakdown Without Altering IGF-1 Pathways?

The question in this article’s title contains a claim and a puzzle folded together, and it is worth separating them before going…

How Orforglipron Works: Its Mechanism Step by Step

Orforglipron switches on the GLP-1 receptor from a binding pocket inside the membrane — a site the natural hormone never touches.1 That…