Adamax (10mg Vial) Dosage Protocol
Adamantane-modified Semax analog studied as a nootropic — obscure research peptide, not approved; documented research use is intranasal.
Pre-filled with this protocol’s recommended BAC water and documented starting dose — edit any field to run your own numbers. Reconstitution math only — not dosing advice. U-100 syringe: 100 units = 1 mL. Full reconstitution guide → · Advanced calculator →Mix & measure Adamax · 10 mg
Dosing & Reconstitution Guide
A single practical dilution with accurate once-daily dosing, step by step
Standard / Gradual Approach (3 mL = ~3.33 mg/mL)
Reconstitute: Add 3.0 mL bacteriostatic water to one 10 mg vial → final concentration ~3.33 mg/mL (3,333 mcg/mL).
Typical daily range: 300–1000 mcg once daily, raised gradually over an 8-week course.
Easy measuring: At ~3.33 mg/mL, 1 unit ≈ 33.3 mcg on a U-100 syringe. The 3.0 mL dilution keeps doses on readable insulin-syringe marks (300 mcg = 9 units up to 1000 mcg = 30 units).
Storage: Lyophilized: store at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and do not freeze the mixed solution.
Why Adamax draws research interest
These are the directions researchers and the peptide community most often explore Adamax for — so you know you’re in the right place. They describe what is being studied, not proven benefits, approved uses, or promised results.
Cognition & nootropic
Explored in research on memory, learning and mental performance as an adamantane-modified Semax analog; investigational, not approved.
Neuroprotection
Studied in preclinical research on protecting neurons from stress and injury, a theme common to Semax-family peptides; animal-level only.
Focus & mental clarity
Investigated for attention and alertness effects reported anecdotally for Semax analogs; obscure compound with very limited documented data.
Mood & stress resilience
Researched as a possible modulator of stress response and mood, extrapolated from Semax BDNF studies; preclinical and unverified for Adamax.
Evidence ranges from early laboratory work to clinical trials depending on the use — the sections below cover the actual data and sources.
Quickstart Highlights
Adamax is a claimed adamantane-modified analog of Semax — Semax being an ACTH(4–10)-derived heptapeptide studied as a nootropic and neuroprotective agent[1][2]. The adamantane cage is claimed to improve peptide stability and blood–brain-barrier penetration, but the evidence is preclinical/animal and drawn from obscure Russian-lab and vendor sources — potency and “superiority over Semax” claims are unverified. Adamax is an unapproved research chemical, not a medicine, and is approved by no regulator; documented research use of this class is intranasal, whereas this page describes subcutaneous injection. Presented for research and educational use only.
Add 3.0 mL bacteriostatic water to one 10 mg vial → ~3.33 mg/mL (3,333 mcg/mL), a practical dilution for clear insulin-syringe measurements.
300–1000 mcg once daily, titrated upward gradually across an 8-week course (Weeks 1–2 start at 300 mcg).
At ~3.33 mg/mL, 1 unit ≈ 33.3 mcg; 300 mcg = 9 units and 1000 mcg = 30 units on a U-100 syringe.
Lyophilized: store at −20 °C (−4 °F); once reconstituted, refrigerate at 2–8 °C (35.6–46.4 °F) and do not freeze the solution.
Important: Start with the Prep & Injection Guide — it covers the preparation and safety basics every protocol on this site assumes.
Frequency: one subcutaneous injection each day (preferably morning), titrating up as tolerated over the 8-week course. Route note: the documented research use of Semax-class peptides is intranasal (a single morning dose, roughly 5–15 mg/day), and a 10 mg vial actually fits mg-scale intranasal dosing better than the 300–1000 mcg/day subcutaneous schedule shown here[3][4]. These figures come from obscure reference protocols, not from approved human dosing.
Reconstitution Steps
Draw 3.0 mL of bacteriostatic water into a sterile syringe.
Release it slowly down the vial’s inner wall to limit foaming.
Swirl or roll gently until fully dissolved — don’t shake.
Label with the date and concentration, then refrigerate at 2–8 °C (35.6–46.4 °F), shielded from light.
The 3.0 mL dilution keeps doses on readable U-100 syringe marks (9 units at the 300 mcg start, up to 30 units at 1000 mcg). Avoid freezing the reconstituted solution, since freeze–thaw can denature the peptide.
Supplies Needed
Quantities below assume an 8–16 week course of once-daily injections with gradual titration.
At this once-daily schedule a 10 mg vial covers roughly two weeks of dosing, so plan a vial every other week.
- 8 weeks: ~4 vials
- 12 weeks: ~7 vials
- 16 weeks: ~9 vials
- Per injection: 1 syringe
- 8 weeks (once daily): ~56 syringes
- 16 weeks (once daily): ~112 syringes
Use ~3.0 mL per 10 mg vial for reconstitution.
- 8 weeks (4 vials): ~12 mL → 2 bottles
- 16 weeks (9 vials): ~27 mL → 3 bottles
One for the vial stopper + one for the injection site each day.
- Per injection: 2 swabs
- 8 weeks (once daily): ~112 swabs → 1–2 boxes
Protocol Overview
A concise summary of the once-daily regimen, drawn from commonly cited reference protocols.
- ▪Goal: Explore claimed nootropic and neuroprotective effects attributed to Semax-class peptides (proposed BDNF/TrkB upregulation) — effects described only in preclinical/animal and obscure-vendor sources, not established in humans[4][5].
- ▪Schedule: Daily subcutaneous injections for 8–12 weeks, optionally extended to ~16 weeks for longer research goals.
- ▪Dose Range: 300–1000 mcg per day subcutaneously with gradual titration (note: documented research use of this class is intranasal at mg-scale doses, not SC microgram doses).
- ▪Reconstitution: 3.0 mL bacteriostatic water per 10 mg vial gives ~3.33 mg/mL for accurate unit measurements.
- ▪Storage: Keep the dry vial frozen at −20 °C (−4 °F); once mixed, refrigerate at 2–8 °C and do not freeze the solution.
Dosing Protocol
A suggested daily titration approach based on common reference doses.
- ▪Start: Begin at 300 mcg once daily (Weeks 1–2) to gauge tolerability.
- ▪Titrate: Increase to 500 mcg (Weeks 3–4), then 750 mcg (Weeks 5–6), as tolerated.
- ▪Target: Reach 1000 mcg daily by Weeks 7–8.
- ▪Cycle Length: Typically an 8-week course; some obscure references extend to ~12–16 weeks.
- ▪Timing: Inject at a consistent time each day and rotate injection sites systematically.
Storage Instructions
Correct storage is what preserves the peptide’s stability and activity.
- ▪Lyophilized: Hold the dry vial at −20 °C (−4 °F) in dry, dark conditions and limit moisture exposure[7].
- ▪Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F) and use within about 28 days; do not freeze the mixed solution, as freezing can denature peptides[8].
- ▪Handling: Let frozen vials warm to room temperature before opening so condensation won’t form, and keep the solution clear of heat and direct light.
- ▪Freeze–thaw: Avoid repeated freeze–thaw cycles of the reconstituted solution.
Important Notes
Practical points that keep daily administration safe and consistent.
- ▪Sterile technique: Use a fresh sterile U-100 insulin syringe each time and drop it straight into a puncture-proof sharps container afterward.
- ▪Site rotation: Move between abdomen, thighs and upper arms to reduce local irritation and lipohypertrophy[9].
- ▪Slow injection: Push the plunger slowly and pause a few seconds before withdrawing the needle to prevent backflow.
- ▪Recordkeeping: Log the daily dose, injection site and any observations to keep the protocol consistent.
- ▪Regulatory note: Adamax is approved by no regulator (FDA, EMA or MHRA); the parent Semax is approved only in Russia/CIS, not the West. As an unapproved substance it falls under WADA category S0 and is not permitted in sport[10].
How This Works
Adamax is described as an adamantane-modified analog of Semax, where Semax is itself a heptapeptide derived from ACTH(4–10)[1][2]. The adamantane cage is claimed to add lipophilicity and enzymatic stability over plain Semax.
Its proposed mechanism is upregulation of BDNF and TrkB signalling together with modulation of melanocortin and dopaminergic/serotonergic systems — the pathways credited with Semax’s claimed nootropic and neuroprotective effects. The adamantane cage is claimed to improve blood–brain-barrier penetration and prolong half-life[4][5].
The parent Semax has animal and limited Russian clinical data for cognition and stroke recovery[7], but the specific adamantane analog “Adamax” appears only in obscure Russian-lab and vendor write-ups; claims that it is 2–3× more potent than Semax are unverified and not supported by independent peer-reviewed data[3].
Important caveat: there is no robust peer-reviewed human data on Adamax specifically. What human evidence exists is for Semax (approved only in Russia/CIS), and even the route differs — documented research dosing of this class is intranasal, not subcutaneous. The nootropic and “superiority” claims here rest on obscure sources and should be read as unverified hypotheses.
Adamax is not an approved medicine anywhere. It is an unapproved research chemical presented here for research and educational purposes only.
Lifestyle Factors
Habits that may support cognitive function alongside the protocol.
- ▪Nutrition: Favour a nutrient-dense diet with omega-3 fatty acids, antioxidants and B vitamins to support brain health.
- ▪Activity & rest: Regular aerobic and resistance exercise may support BDNF expression; balance with real recovery time.
- ▪Sleep: Aim for 7–9 hours nightly to support memory consolidation and neural recovery.
- ▪Stress: Manage stress with evidence-based practices (meditation, breathwork), since it influences cognition and mood.
Potential Benefits & Side Effects
What preclinical and obscure-source literature describe; robust human evidence is lacking and individual results vary.
Potential Benefits
- ▪Cognition (preclinical): Semax-class peptides are described as improving learning and memory via BDNF/TrkB upregulation in animal models[4][5].
- ▪Neuroprotection (preclinical): Semax has been linked to neuronal survival in ischemic and oxidative-stress animal models[8].
- ▪Mood (preclinical): Modulation of dopamine and serotonin systems is proposed to support stress resilience — reported in animal work, not confirmed in humans.
- ▪Note on humans: These benefits are not established for Adamax in humans — no robust trials of this adamantane analog have been completed; the parent Semax is approved only in Russia/CIS[9].
Common Side Effects
- ▪Injection-site reactions: Mild redness, tenderness or soreness can occur with subcutaneous use; rotating sites helps.
- ▪Unknown long-term profile: Human safety data for Adamax is essentially absent (extrapolated from Semax), so caution and monitoring are advised.
- ▪Sport restriction: As an unapproved substance, Adamax falls under WADA category S0 and is prohibited in sport.
Injection Technique
General subcutaneous technique, following established clinical best-practice guidance[14][15].
Pre-Injection Preparation
- ▪Wash your hands well with soap and water.
- ▪Wipe the vial stopper with an alcohol swab and let it air-dry.
- ▪Choose a site (abdomen, thigh, or upper arm) and clean it with a fresh alcohol swab, letting it dry fully[15].
- ▪Draw the intended dose, then check for air bubbles and push any out.
Injection Procedure
- ▪Pinch a skinfold at the chosen site between thumb and forefinger.
- ▪Insert the needle into the pinch at a 45–90-degree angle (use 45 degrees if the fat layer is thin)[14].
- ▪Skip aspiration for subcutaneous shots — it isn’t needed[14].
- ▪Press the plunger slowly and steadily until it’s fully down.
- ▪Wait 5–10 seconds, then pull the needle straight out to prevent leakage.
Post-Injection Care
- ▪Drop the used syringe straight into a puncture-proof sharps container — never recap a needle.
- ▪Return the reconstituted vial to the fridge right away.
- ▪Rotate the injection site each day to prevent irritation and lipohypertrophy[9].
- ▪Watch the site for excess redness, swelling, or signs of infection.
Recommended Source
For high-purity research peptides, we point researchers to Prime Lab Peptides for Adamax (10 mg).
Why Prime Lab Peptides?
- ▪Top-rated on Trustpilot: Independently reviewed as the highest-rated peptide lab on Trustpilot — making it the best current source in the USA.
- ▪Third-party tested: Every batch ships with a Certificate of Analysis (COA) confirming purity and composition.
- ▪Consistent quality: ISO-aligned manufacturing and handling keep product integrity reliable batch to batch.
- ▪Cold-chain integrity: Temperature-controlled shipping and storage across the whole fulfilment chain.
- ▪Research-grade purity: Fit for educational and research use that demands high-quality peptides.
Note: Product availability and specifications subject to change. Verify current product details on supplier website.
References
- 1
PubMedSemax: structure and mechanism — an ACTH(4–10)-derived heptapeptide studied as a nootropic.
- 2
PMC (NCBI)ACTH(4–10) analogs: neuroprotective and cognitive effects of the Semax family.
- 3
Vendor / Russian-lab sources (unverified)The adamantane-modified analog “Adamax” and its claimed 2–3× potency over Semax appear only in obscure vendor and Russian-lab write-ups — not independently verified.
- 4
Journal of NeurochemistrySemax increases BDNF protein and modulates TrkB signalling in rat brain (proposed nootropic mechanism).
- 5
Neuroscience and Behavioral PhysiologyBDNF and TrkB modulation by ACTH analogs — proposed neuroplasticity mechanisms.
- 6
PubMedSemax effects on dopamine and serotonin neurotransmission (mood and cognition).
- 7
Bulletin of Experimental Biology and MedicineSemax improves learning and memory in animal models (Russian experimental literature).
- 8
- 9
Semax (Russia/CIS regulatory status)Semax is registered as a medicine in Russia/CIS only; Adamax is approved by no regulator (FDA/EMA/MHRA).
- 10
WADA Prohibited ListUnapproved substances (category S0) are prohibited in sport at all times — this includes research peptides such as Adamax.
- 11
Medicinal Chemistry literatureAdamantane modification of peptides claimed to enhance stability and CNS penetration (general principle; not Adamax-specific human data).
- 12
PubMedIntranasal Semax: pharmacokinetics and the intranasal route documented for this peptide class.
- 13
ClinicalTrials.govTrial registry search for Semax/Adamax — no completed Western efficacy trials of this peptide class.
- 14
Centers for Disease Control and Prevention (CDC)Subcutaneous injection technique: angle, site and no-aspiration guidance.
- 15
Subcutaneous Injection Technique (Patient Education)How to administer a subcutaneous injection: clinical technique guidelines.
- 16
Prime Lab PeptidesSupplier homepage — research-peptide purity specifications and certificates of analysis.
Adamax — frequently asked questions
How do I reconstitute a 10 mg vial of Adamax?
Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units.
How much bacteriostatic water should I add to Adamax?
There is no single correct amount — more water simply spreads the same 10 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units.
What do the "units" on an insulin syringe mean?
On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand.
How should I store Adamax after mixing?
Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product.
How many doses does a 10 mg vial of Adamax provide?
Divide the vial strength of 10 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose.
Is Adamax approved for human use?
No. Adamax is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.
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