Prostamax (20mg Vial) Dosage Protocol
Khavinson prostate short-peptide bioregulator (KEDP) — research-only; not approved, benefits unproven.
Pre-filled with this protocol’s recommended BAC water and documented starting dose — edit any field to run your own numbers. Reconstitution math only — not dosing advice. U-100 syringe: 100 units = 1 mL. Full reconstitution guide → · Advanced calculator →Mix & measure Prostamax · 20 mg
Dosing & Reconstitution Guide
A single practical dilution with accurate once-daily dosing, step by step
Standard / Gradual Approach (3 mL = ~6.67 mg/mL)
Reconstitute: Add 3.0 mL bacteriostatic water to one 20 mg vial → final concentration ~6.67 mg/mL (6,667 mcg/mL).
Typical daily range: 500–3,000 mcg once daily, raised stepwise over a 12-week course.
Easy measuring: At ~6.67 mg/mL, 1 unit ≈ 66.7 mcg on a U-100 syringe. The full 3.0 mL dilution keeps the maintenance doses in a 15–45 unit range that is easy to read; the lowest 500 mcg dose sits near 7.5 units, so measure it carefully.
Storage: Lyophilized: store at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and do not freeze the mixed solution.
Why Prostamax draws research interest
These are the directions researchers and the peptide community most often explore Prostamax for — so you know you’re in the right place. They describe what is being studied, not proven benefits, approved uses, or promised results.
Prostate health & function
The primary reason people look into it: explored in Khavinson bioregulator research on prostate tissue; not approved, benefits unproven.
Prostatitis & inflammation
Investigated in preclinical work on prostatic inflammation as a short-peptide (KEDP) bioregulator; animal-only, not clinically validated.
Lower urinary tract function
Researched in the context of age-related prostate changes and urinary flow; investigational, no approved indication.
Male reproductive support
Studied in Khavinson peptide-bioregulator research on male reproductive tissue; preclinical framing only, benefits unproven.
Evidence ranges from early laboratory work to clinical trials depending on the use — the sections below cover the actual data and sources.
Quickstart Highlights
Prostamax is a synthetic tetrapeptide KEDP (Lys-Glu-Asp-Pro), one of the Khavinson short-peptide bioregulators developed in Russia and presented as the defined-sequence synthetic successor to the older bovine prostate extract Prostatilen/Vitaprost — a different product whose data should not be transferred to Prostamax[1][5]. This educational page outlines a once-daily subcutaneous approach with a dilution chosen so doses land on easy-to-read insulin-syringe marks. It is an unapproved research chemical, not a medicine; evidence for synthetic KEDP is weak and preclinical, with no independent replication and no Western clinical trial — presented for research and educational use only.
Add 3.0 mL bacteriostatic water to one 20 mg vial → ~6.67 mg/mL (6,667 mcg/mL), the largest practical dilution for accurate dosing.
500–3,000 mcg once daily, stepped up gradually across a 12-week course (rising from ~3.5 mg/week early to ~21 mg/week at the top dose).
At ~6.67 mg/mL, 1 unit ≈ 66.7 mcg; 500 mcg ≈ 7.5 units and the top dose of 3,000 mcg ≈ 45 units on a U-100 syringe.
Lyophilized: store at −20 °C (−4 °F); once reconstituted, refrigerate at 2–8 °C (35.6–46.4 °F) and do not freeze the solution.
Important: Start with the Prep & Injection Guide — it covers the preparation and safety basics every protocol on this site assumes.
Frequency: one subcutaneous injection each day, titrating up as tolerated. Across the cycle the weekly total climbs from roughly 3.5 mg/week early to about 21 mg/week at the 3,000 mcg maintenance dose — a cautious extrapolation, since published human dosing data for synthetic Prostamax are limited[3][4]. These figures come from reference protocols, not from approved human dosing.
Reconstitution Steps
Draw 3.0 mL of bacteriostatic water into a sterile syringe.
Release it slowly down the vial’s inner wall to limit foaming.
Swirl or roll gently until fully dissolved — don’t shake.
Label with the date and concentration, then refrigerate at 2–8 °C (35.6–46.4 °F), shielded from light.
The 3.0 mL dilution is chosen so the higher maintenance doses read at 30–45 units, where U-100 syringe markings are most precise; the lowest 500 mcg starting dose is only ~7.5 units, so draw it with extra care. Avoid freezing the reconstituted solution, since freeze–thaw can denature the peptide.
Supplies Needed
Quantities below assume an 8–16 week course of once-daily injections with gradual titration.
A 20 mg vial covers a little over one week of dosing at the higher end of the titration (about ~14 mg/week by weeks 7–12), so plan a little under one vial per week on average.
- 8 weeks: ~6 vials
- 12 weeks: ~9 vials
- 16 weeks: ~12 vials
- Per injection: 1 syringe
- 8 weeks (once daily): ~56 syringes
- 16 weeks (once daily): ~112 syringes
Use ~3.0 mL per 20 mg vial for reconstitution.
- 8 weeks (~6 vials): ~18 mL → 2 bottles
- 16 weeks (~12 vials): ~36 mL → 4 bottles
One for the vial stopper + one for the injection site each day.
- Per injection: 2 swabs
- 8 weeks (once daily): ~112 swabs → 1–2 boxes
Protocol Overview
A concise summary of the once-daily regimen, drawn from commonly cited reference protocols.
- ▪Goal (hypothesized): A proposed prostate-targeting short-peptide bioregulator (KEDP) — the Khavinson school’s gene-expression hypothesis, supported only by weak preclinical data and not established in humans[5][6].
- ▪Schedule: Once-daily subcutaneous injections for a 12-week course, with the dose stepped up every two weeks.
- ▪Dose Range: 500–3,000 mcg per day with stepwise titration over 12 weeks.
- ▪Reconstitution: 3.0 mL bacteriostatic water per 20 mg vial gives ~6.67 mg/mL (1 unit ≈ 66.7 mcg) for unit measurement.
- ▪Storage: Keep the dry vial frozen at −20 °C (−4 °F); once mixed, refrigerate at 2–8 °C and do not freeze the solution.
Dosing Protocol
A suggested daily titration approach based on common reference doses.
- ▪Start: Begin at 500 mcg once daily (weeks 1–2) to gauge tolerability.
- ▪Titrate: Step up roughly every two weeks (1,000 mcg at weeks 3–4, then 2,000 mcg at weeks 5–6) as tolerated.
- ▪Target: Reach the 3,000 mcg daily maintenance dose by weeks 7–12.
- ▪Cycle Length: A single 12-week course is the schedule modelled here.
- ▪Timing: Inject at a consistent time each day and rotate injection sites systematically.
Storage Instructions
Correct storage is what preserves the peptide’s stability and activity.
- ▪Lyophilized: Hold the dry vial at −20 °C (−4 °F) in dry, dark conditions and limit moisture exposure[7].
- ▪Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F) and use within about 28 days; do not freeze the mixed solution, as freezing can denature peptides[8].
- ▪Handling: Let frozen vials warm to room temperature before opening so condensation won’t form, and keep the solution clear of heat and direct light.
- ▪Freeze–thaw: Avoid repeated freeze–thaw cycles of the reconstituted solution.
Important Notes
Practical points that keep daily administration safe and consistent.
- ▪Sterile technique: Use a fresh sterile U-100 insulin syringe each time and drop it straight into a puncture-proof sharps container afterward.
- ▪Site rotation: Move between abdomen, thighs and upper arms to reduce local irritation and lipohypertrophy[9].
- ▪Slow injection: Push the plunger slowly and pause a few seconds before withdrawing the needle to prevent backflow.
- ▪Recordkeeping: Log the daily dose, injection site and any observations to keep the protocol consistent.
- ▪Regulatory note: Prostamax is not FDA- or EMA-approved; as a peptide it falls under WADA’s S0 (non-approved substances) catch-all and is prohibited in sport[10].
How This Works
Prostamax is a synthetic tetrapeptide with the sequence Lys-Glu-Asp-Pro (KEDP)[1][2]. It belongs to the family of Khavinson short-peptide bioregulators — short, defined-sequence peptides proposed by the Russian Khavinson school to act on specific tissues, with KEDP framed as the prostate-targeting member.
The school’s proposed mechanism is that such short peptides enter cells and bind regions of DNA to modulate gene expression in their target tissue[5][6]. This chromatin/gene-expression model is a hypothesis from that research program; it has not been robustly demonstrated for synthetic KEDP independently, and the supporting work is largely preclinical (rat prostatitis models and cell culture) without independent replication.
Prostamax is presented as the defined-sequence synthetic successor to the older bovine prostate extract Prostatilen/Vitaprost[11]. That extract is a different product: it holds Russian pharmaceutical registration and has its own human clinical literature, whereas the human data for synthetic KEDP are weak and preclinical[12]. The two should not be conflated, and Prostatilen/Vitaprost trial results must not be transferred to Prostamax.
Important caveat: there are no Western randomized controlled trials of synthetic Prostamax (KEDP), and no independent replication of the proposed prostate effects. Claims of prostate “rejuvenation,” BPH or urinary improvement, or anti-aging benefit are not established and should be read as unproven hypotheses.
In Russia, Prostamax is sold as a dietary supplement (БАД), not a registered drug, and it is not FDA- or EMA-approved anywhere. It is an unapproved research chemical presented here for research and educational purposes only.
Lifestyle Factors
General wellness habits some researchers pair with the protocol; none of these are established to interact with Prostamax.
- ▪Nutrition: Keep a balanced, nutrient-adequate diet; no specific food is established to interact with this peptide.
- ▪Activity & rest: Maintain regular activity and adequate rest as part of general wellness.
- ▪Sleep: Aim for 7–9 hours to support overall health.
- ▪Stress: Manage stress with evidence-based practices for general wellbeing.
Potential Benefits & Side Effects
What the limited preclinical literature describes; there is no robust human evidence, and these are unproven hypotheses.
Potential Benefits
- ▪Prostate models (preclinical): Small rat prostatitis studies and cell-culture work from the Khavinson program report effects on prostate tissue[5][6]; these are weak, not independently replicated, and do not establish a benefit.
- ▪Proposed mechanism (hypothesis): A chromatin/gene-expression effect in prostate tissue has been proposed for KEDP[11], but it has not been robustly demonstrated for the synthetic peptide independently.
- ▪Not Prostatilen/Vitaprost: Do not borrow the bovine extract’s human data — that is a different, registered product, and its results do not apply to synthetic Prostamax.
- ▪Note on humans: Any prostate “rejuvenation,” BPH, urinary or anti-aging benefit is not established in humans — no Western RCT of synthetic KEDP has been completed[13].
Common Side Effects
- ▪Injection-site reactions: Mild redness, tenderness or soreness can occur; rotating sites helps.
- ▪Unknown long-term profile: Human safety data is limited, so caution and monitoring are advised.
- ▪Sport restriction: As a non-approved peptide, Prostamax falls under WADA’s S0 catch-all and is prohibited in sport.
Injection Technique
General subcutaneous technique, following established clinical best-practice guidance[14][15].
Pre-Injection Preparation
- ▪Wash your hands well with soap and water.
- ▪Wipe the vial stopper with an alcohol swab and let it air-dry.
- ▪Choose a site (abdomen, thigh, or upper arm) and clean it with a fresh alcohol swab, letting it dry fully[15].
- ▪Draw the intended dose, then check for air bubbles and push any out.
Injection Procedure
- ▪Pinch a skinfold at the chosen site between thumb and forefinger.
- ▪Insert the needle into the pinch at a 45–90-degree angle (use 45 degrees if the fat layer is thin)[14].
- ▪Skip aspiration for subcutaneous shots — it isn’t needed[14].
- ▪Press the plunger slowly and steadily until it’s fully down.
- ▪Wait 5–10 seconds, then pull the needle straight out to prevent leakage.
Post-Injection Care
- ▪Drop the used syringe straight into a puncture-proof sharps container — never recap a needle.
- ▪Return the reconstituted vial to the fridge right away.
- ▪Rotate the injection site each day to prevent irritation and lipohypertrophy[9].
- ▪Watch the site for excess redness, swelling, or signs of infection.
Recommended Source
For high-purity research peptides, we point researchers to Prime Lab Peptides for Prostamax (20 mg).
Why Prime Lab Peptides?
- ▪Top-rated on Trustpilot: Independently reviewed as the highest-rated peptide lab on Trustpilot — making it the best current source in the USA.
- ▪Third-party tested: Every batch ships with a Certificate of Analysis (COA) confirming purity and composition.
- ▪Consistent quality: ISO-aligned manufacturing and handling keep product integrity reliable batch to batch.
- ▪Cold-chain integrity: Temperature-controlled shipping and storage across the whole fulfilment chain.
- ▪Research-grade purity: Fit for educational and research use that demands high-quality peptides.
Note: Product availability and specifications subject to change. Verify current product details on supplier website.
References
- 1
Khavinson V.Kh. (review)Overview of the Khavinson short-peptide bioregulators, including the tetrapeptide KEDP (Lys-Glu-Asp-Pro) proposed for prostate tissue.
- 2
PubMed (search)Literature on short regulatory peptides (KED/KEDP family) and the proposed peptide-DNA interaction model.
- 3
Dosing note (educational)The microgram schedule shown is a cautious educational extrapolation; published human dosing data for synthetic Prostamax (KEDP) are limited.
- 4
Prostatilen / Vitaprost (distinct product)Russian-registered bovine prostate extract Prostatilen/Vitaprost — a different product whose human data should NOT be transferred to synthetic Prostamax.
- 5
PubMed (preclinical)Preclinical (rat prostatitis / cell-culture) studies of short prostate peptides; weak evidence, no independent replication.
- 6
PubMed (mechanism hypothesis)Proposed peptide-DNA / gene-expression mechanism of Khavinson peptides — a hypothesis not robustly demonstrated for synthetic KEDP independently.
- 7
Peptide Storage GuideBest practices for storing lyophilized peptides (temperature, humidity and light protection).
- 8
Bacteriostatic Water GuidanceBacteriostatic water for injection: multi-dose vial stability and handling.
- 9
NCBI BookshelfBest practices for subcutaneous injection: aseptic technique and site rotation.
- 10
WADA Prohibited ListWADA Prohibited List — non-approved substances (S0) catch-all covers research peptides such as Prostamax in competitive sport.
- 11
PubMed (extract vs. synthetic)Background distinguishing the registered bovine extract Prostatilen/Vitaprost from synthetic KEDP (Prostamax); their evidence bases are separate.
- 12
PubMed (evidence quality)Evidence for synthetic KEDP is weak and preclinical (rat / cell culture), with no independent replication and no Western RCT.
- 13
ClinicalTrials.govTrial registry search — no completed Western efficacy trials of synthetic Prostamax (KEDP).
- 14
Centers for Disease Control and Prevention (CDC)Subcutaneous injection technique: angle, site and no-aspiration guidance.
- 15
Subcutaneous Injection Technique (Patient Education)How to administer a subcutaneous injection: clinical technique guidelines.
- 16
Prime Lab PeptidesProstamax (20 mg) product page — purity specifications and certificates of analysis.
Prostamax — frequently asked questions
How do I reconstitute a 20 mg vial of Prostamax?
Wipe the stopper with an alcohol swab, then inject your bacteriostatic water slowly down the inside wall of the vial. Let it sit and gently swirl until dissolved — never shake. Store the mixed vial in the refrigerator and draw doses with an insulin syringe. Use the calculator above to turn any dose into syringe units.
How much bacteriostatic water should I add to Prostamax?
There is no single correct amount — more water simply spreads the same 20 mg of peptide across a larger volume, which makes small doses easier to measure accurately. 1 to 3 mL per vial is typical. Enter your chosen volume in the calculator above to see the resulting concentration and syringe units.
What do the "units" on an insulin syringe mean?
On a U-100 insulin syringe, 100 units equal 1 mL, so 1 unit equals 0.01 mL. The calculator above converts your draw volume into these units automatically so you can measure without doing the math by hand.
How should I store Prostamax after mixing?
Keep the reconstituted vial refrigerated at roughly 2 to 8 degrees Celsius, away from light, and avoid freezing it. Reconstituted research peptides are generally used within a few weeks. Always follow the specific guidance supplied with your product.
How many doses does a 20 mg vial of Prostamax provide?
Divide the vial strength of 20 mg by the amount you use per injection. The calculator above reports this as "doses per vial" the moment you enter a dose.
Is Prostamax approved for human use?
No. Prostamax is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use. Everything on this page is research information, not medical advice — consult a licensed healthcare professional before any use.
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