Quickstart Highlights
- Slow, steady dose escalation helps minimize GI side effects
- Once-weekly injection schedule for user convenience
- May be reconstituted to ~3.33 mg/mL or 5 mg/mL for practical dosing
- Store lyophilized vials in the freezer; reconstituted in the refrigerator
- Useful for both gradual titration or higher dosing protocols
Important: Before viewing any protocol, please consult our Prep & Injection Guide for essential preparation and safety instructions.Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing
Standard / Gradual Approach (3 mL ≈ 3.33 mg/mL)
| Phase | Weekly Dose (mg) | Approx. Units |
|---|---|---|
| Weeks 1–2 | 0.25 mg | 7.5 units |
| Weeks 3–4 | 0.5 mg | 15 units |
| Weeks 5–8 | 1.0 mg | 30 units |
| Weeks 9–12 | 1.7 mg | 51 units |
| Weeks 13–16 (Optional) | 2.4 mg | 72 units |
Ideal for moderate doses up to 2.4 mg per week. Reconstitute with 3 mL to create a ~3.33 mg/mL solution.
Reconstitution steps:
- Draw 3.0 mL of bacteriostatic water into a sterile syringe.
- Inject the water slowly along the vial wall to reduce foam.
- Gently swirl—avoid vigorous shaking.
- Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
Advanced / Aggressive Approach (2 mL = 5 mg/mL)
If you prefer ≥10 units for the lowest dose (0.25 mg), consider using half-unit syringes or a more dilute ratio exceeding 3 mL.
| Phase | Weekly Dose (mg) | Approx. Units |
|---|---|---|
| Weeks 1–2 | 0.25 mg | 5 units |
| Weeks 3–4 | 0.5 mg | 10 units |
| Weeks 5–8 | 1.0 mg | 20 units |
| Weeks 9–12 | 1.7 mg | 34 units |
| Weeks 13–16 (Optional) | 2.4 mg | 48 units |
Recommended for higher concentration needs. Reconstitute with 2 mL to create a 5 mg/mL solution. Note that doses below 0.5 mg may be under 10 units on a standard syringe.
- Draw 2.0 mL of bacteriostatic water into a sterile syringe.
- Slowly inject the water to minimize foam.
- Gently roll/swirl the vial—no vigorous shaking.
- Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
Supplies Needed
Ensure you have these on hand for an 8–16 week cycle.
- Peptide Vials:
• 8 wks ≈ 1 vial
• 12 wks ≈ 2 vials
• 16 wks ≈ 3 vials
(Additional vials if planning higher doses) - Insulin Syringes:
• 8 wks ≈ 8
• 12 wks ≈ 12
• 16 wks ≈ 16 - Bacteriostatic Water: 1× 30ml
- Alcohol Swabs: 1 box
![Peptide Vial](http://www.dosagepeptide.com/wp-content/uploads/2025/12/Cagrilintide10mg001-1-scaled.png" alt="Cagrilintide (10mg Vial)" /></div>)
Protocol Overview
A concise summary of this once-weekly regimen.
- Goal: Promote weight management and metabolic control
- Schedule: Weekly subcutaneous injections, 8–16 weeks or longer
- Dose Range: 0.25 mg to 2.4 mg weekly via escalation
- Reconstitution: ~3.33 mg/mL or 5 mg/mL for flexible dosing
- Storage: Keep lyophilized vials frozen; refrigerate after reconstitution
Dosing Protocol
Suggested once-weekly injection approach for effective titration based on clinical trial data.
- Weekly Dose: Start at 0.25 mg; gradually increase as tolerated
- Frequency: Inject once per week subcutaneously
- Cycle Length: 8–16 weeks (extend longer if needed for maintenance)
- Maximum Dose (Clinical Studies): Up to 4.5 mg weekly in certain trials
- Timing: Administer any time of day; consistency is key
Storage Instructions
Proper storage ensures peptide integrity.
- Lyophilized: Freeze until mixing (−20°C)
- Reconstituted: Refrigerate at 2–8°C
- Use within 30 days of reconstitution
- Avoid repeated freeze-thaw cycles
Important Notes
Practical tips to enhance safety and efficacy.
- Always use new, sterile insulin syringes & rotate injection sites.
- Maintain a consistent once-weekly schedule for optimal results.
- Observe for gastrointestinal side effects; adjust titration if needed.
- Monitor progress regularly, modifying dosage based on professional guidance.
How This Works
Cagrilintide is a long-acting amylin analogue investigated for its impact on appetite and metabolism.
- Amylin Pathway: Modulates gastric emptying and enhances satiety signals
- Metabolic Support: Aims to reduce overall caloric intake and assist weight loss
- Complements insulin function, helping with glucose control
Potential Benefits & Side Effects
Most research participants report improved appetite regulation and moderate weight reduction.
- May contribute to significant reductions in body weight
- Supports improved glycemic control in some populations
- Common side effects: nausea, GI discomfort, or mild injection site reactions
- Serious adverse events are rare but must be monitored
Lifestyle Factors
Complementary strategies for optimal outcomes.
- Focus on balanced, protein-rich nutrition
- Incorporate regular physical activity and recovery practices
- Manage stress and ensure consistent, quality sleep
Injection Technique
Simple guidelines for safe daily injections.
- Clean vial rubber stopper & injection site with alcohol swabs
- Insert needle at a 45–90° angle into subcutaneous tissue
- Inject slowly & rotate sites (abdomen, thigh, etc.)
Recommended Source
We recommend Prime Lab Peptides for high-purity Cagrilintide.
Why Prime Lab Peptides?
- Verifies ≥99% purity through independent lab testing
- Trusted by researchers seeking reliable results
- Follows rigorous manufacturing standards for consistent quality
Important Note
This guide is for educational purposes only. Always consult a qualified healthcare provider before starting or modifying any therapy.